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CAS Clinical Trial Update

Clinical Studies

July 2008
Updates From the Investigators
CREST
Featuring Thomas G. Brott, MD

TACIT
Featuring John Rundback, MD

ACST-2
Featuring Alison Halliday, MD

ACT 1
Featuring Jon S. Matsumura, MD

September 2007
Carotid Artery Stenting Versus Carotid Endarterectomy
By Peter H. Lin, MD; Tam T. Huynh, MD;Panagiotis Kougias, MD; and Hosam F. El-Sayed, MD

Barriers to Carotid Artery Stenting Dissemination
By Gary S. Roubin, MD, PhD

Asymptomatic CAS Trial Designs
A Discussion with John H. Rundback, MD and Sumaira Macdonald, MD

CREST Update
By Susan E. Hughes, BSN; MeeLee Tom, MS; Mary E. Longbottom, BA; Alice J. Sheffet, PhD; Thomas G. Brott, MD; and Robert W. Hobson II, MD

CAS Clinical Trial and Registry Update

August 2006
Update on the TACIT Trial
Endovascular Today interviews John H. Rundback, MD

September 2005
The Asymptomatic Carotid Stenosis Trials
New data support intervention in asymptomatic patients, and a new trial of stenting versus surgery is planned.
By Endovascular Today Staff

The Transatlantic Asymptomatic Carotid Intervention Trial
By Barry T. Katzen, MD, for the TACIT Investigators

January 2005
Carotid Artery Stent Restenosis
By George Younis, MD; Kamal Gupta, MD; Neil Strickman, MD; Ali Mortazavi, MD; Arup Achari, MD; Emerson Perin, MD; and Zvonimir Krajcer, MD

September 2004
The Carotid Issue: Carotid Revascularization in 2004
By Thomas G. Brott, MD; Jamie Roberts, LPN, CRC; Robert W. Hobson II, MD; and Susan Hughes, BSN

The CREST Trial Update
By Susan Hughes, BSN; Jamie Roberts, LPN, CRC; Thomas G. Brott, MD; Robert W. Hobson II, MD; and Alice Sheffet, PhD, for the CREST Investigators

July / August 2004
CAS Using the Wallstent/FilterWire EX/EZ
By Marc Bosiers, MD; Patrick Peeters, MD; Jurgen Verbist, MD; and Koen Deloose, MD

January 2004
The CARESS Trial
This groundbreaking study sponsored by the International Society for Endovascular Specialists (ISES) involving collaboration among industry, the FDA, and CMS, is the first to address a broad range of symptomatic and asymptomatic carotid lesions.
By The ISES Steering Committee: Edward B. Diethrich, MD, Thomas Fogarty, MD, L. Nelson Hopkins, MD, Gary Roubin, MD, PhD, Rodney White, MD, (Chairman), Mark H. Wholey, MD, and Christopher Zarins, MD

September 2003
The SAPPHIRE and ARCHeR Updates
A report on the early progress of two trials critical to our understanding of carotid artery stenting.
By Barry T. Katzen, MD; John R. Laird, Jr, MD; and Takao Ohki, MD, PhD

May / June 2003
The ARCHeR Trial: 30-Day Results
Experience with carotid stenting in high surgical risk patients compares favorably with historical CEA outcomes.
By Alicia Fagan

September 2002
A Review of Current Carotid Artery Stent Trials
CAS for high-surgical-risk patients will most likely be approved in the coming year.
By Jay Yadav, MD